One of the most important of the secondary causes of osteoporosis is chronic exposure to glucocorticoids, which are used for an extraordinarily large number of disorders. The adverse effects of hypercortisolism on bone metabolism were recognized more than half a century ago ( 1 ).

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osteoporosis. 3. Engdahl C et al. Östrogen skyddar mot artrit och inflammationsmedierad benförlust via östrogen receptor alfa. 4. Klingberg E et al. Impaired 

Pathogenesis of osteoporosis Menopausal hormone therapy in the prevention and treatment of osteoporosis Screening for osteoporosis in postmenopausal women and men Treatment of osteoporosis in men Use of biochemical markers of bone turnover in osteoporosis. The following organizations also provide reliable health information. The following is an organ-system based review of the pathogenesis and diagnostic considerations of the more common causes of secondary osteoporosis. Please note that genetic bone diseases, male osteoporosis, renal osteodystrophy, and treatment considerations are not included in this review. The pathogenesis of secondary osteoporosis is almost always multifactorial. Certain endocrinopathies, systemic diseases, malignant neoplasias, organ dysfunctions, a variety of medications such as corticosteroids, lifestyle conditions and habits, and also major depression can lead to the secondary osteoporosis.

Secondary osteoporosis pathogenesis

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[Secondary osteoporosis. Pathogenesis of glucocorticoid-induced osteoporosis] Clin Calcium. 2007 Feb;17(2):270-4. [Article in Japanese] Author Secondary osteoporosis can be caused by an identifiable agent such as glucocorticoids, or by a disease such as hyperthyroidism or myeloma. Although there are many causes of osteoporosis, the most common cause is oestrogen deficiency in postmenopausal women [3-5].

11 Dec 2013 Osteoporosis is a deterioration in the structural integrity of bone and loss of bone density due to demineralization that eventually causes fragile 

av C LINDÉN · Citerat av 17 — prospective controlled paediatric osteoporosis prevention (POP) study is Secondary osteoporosis is the result of negative feedback mechanism that involves. av O Ahlgren · 1975 — OSTEOPOROSIS.

Secondary osteoporosis pathogenesis

Self performed treatment in female cancer survivors with secondary lymphedema  Physical activity and health-related quality of life in older adults with osteoporosis  and play important roles in breast cancer pathogenesis and evolution.

Secondary osteoporosis pathogenesis

Characterisation of its pathophysiology from the hierarchical structure of bone and the role of its cell population, development of The mechanisms of secondary forms of osteoporosis have been explored. Nevertheless, there is still considerable controversy concerning pathogenesis, and there are many gaps in our knowledge. There has also been confusion concerning terminology. 2015-04-21 · The pathogenesis of primary osteoporosis is complex and influenced by both environmental and genetic factors. Oxidative stress, apoptosis, sex-steroid deficiency and macroautophagy are age-related One of the most important of the secondary causes of osteoporosis is chronic exposure to glucocorticoids, which are used for an extraordinarily large number of disorders. The adverse effects of hypercortisolism on bone metabolism were recognized more than half a century ago ( 1 ). Secondary osteoporosis is defined as low bone mass with microarchitectural alterations in bone leading to fragility fractures in the presence of an underlying disease or medication .

Secondary osteoporosis pathogenesis

Please note that genetic bone diseases, male osteoporosis, renal osteodystrophy, and treatment considerations are not included in this review. [Secondary osteoporosis.
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Molecular Pathways Involved in the Pathogenesis and Behavior of Mesenchymal Villkor: Vitamin D Deficiency; Secondary Hyperparathyroidism; Osteomalacia Villkor: Rotator Cuff Tear Arthropathy; Osteoporosis; Osteomalacia; Joint;  av D Chantzichristos · 2018 · Citerat av 1 — induce long-term side effects such as osteoporosis, obesity, hypertension and type 2 diabetes prospective study in patients with primary and secondary adrenal first 10 years after diagnosis, the leading cause of death was acute diabetic. in a well state, secondary to reports of glucose regulation abnormalities in SMA. and disease severity, and to explore the underlying molecular pathogenesis. as muscle atrophy, muscle weakness and osteoporosis-symptoms associated  av R Kawata · 2021 — We set an observation period of one week to prevent the secondary effects of high To clarify the molecular mechanism underlying the changes in cholinergic cardiovascular disease, stroke, renal impairment, osteoporosis, and stomach  av K Larsson — Definition and diagnosis of pulmonary diseases with special secondary care.

14. van Hecke, O., Polymyalgia rheumatica -- diagnosis and management.
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Senile osteoporosis has been recently recognized as a geriatric syndrome with a particular pathophysiology. There are different classification of osteoporosis: primary, in which bone loss is a result of aging and secondary, in which bone loss occurs from various clinical and lifestyle factors.

Secondary osteoporosis may result from endocrine abnormalities, such as hyperthyroidism, hypogonadism, Cushing's syndrome (see Chapters 45 and 46), and hyperparathyroidism (see Chapter 50). In addition, some chronic conditions, such as malabsorption, immobilization, hepatic, and renal disease (see Chapter 49) can result in bone loss. Secondary causes of bone loss are not often considered in patients who are diagnosed as having osteoporosis. In some studies, 20% to 30% of postmenopausal women and more than 50% of men with osteoporosis have a secondary cause.

Secondary osteoporosis results from specific clinical disorders that are potentially reversible. Up to 30% of postmenopausal women and 50% of men with osteoporosis may have an underlying cause. The underlying pathogenesis of secondary osteoporosis is often multifactorial. Correctly treating the cause may ameliorate fracture risk and avoid

Radiologe. 2011 Apr;51(4):307-24.

14. van Hecke, O., Polymyalgia rheumatica -- diagnosis and management. Aust. Diagnosis and management of osteoporosis in postmenopausal women: clinical Secondary osteoporosis In various studies, 30-60% of men evaluated for  pathogenesis of this type of fracture is still poorly understood. We present osteoporotic fractures in postmenopausal nic postmenopausal women: secondary. Clinical efficacy of imaging modalities in the diagnosis of Secondary gain concept: definition problems and Osteoporosis of the slender smoker. Arch Intern  av R Anderson — recommendations for the diagnosis and treatment of chronic pancreatitis: part 2 bile duct stenosis secondary to chronic pancreatitis: comparison of single vs.